anti-BCMA antibody
Key features and details
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- 抗原物种:
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CAT.NO. : ARG54594
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCMA |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody recognizes human BCMA(B Cell Maturation Protein). BCMA is areceptor for BAFF and April, two novelmembers of the TNF superfamily ofproteins regulating immune responseand the induction of apoptosis throughthe activation of NF-κB and c-jun Nterminalkinase. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCMA |
| 抗原物种 | Human |
| 抗原 | A synthetic peptide corresponding to the C-terminus of Human BCMA. |
| 偶联标记 | Un-conjugated |
| 別名 | BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A |
应用说明
| 应用说明 | Western blot: Use at 2 - 5 ug/ml. A band of approximately 27 kD is detected using K562 cell lysate as a positive control. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|---|
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17 |
|---|---|
| 基因名称 | TNFRSF17 |
| 全名 | tumor necrosis factor receptor superfamily, member 17 |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [UniProt] |
| 研究领域 | Cancer antibody; Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 20 kDa |
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