anti-Bestrophin 3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG10775
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Bestrophin 3 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Bestrophin 3 |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide taken within the last 50 aa (C-terminus) from Rat Bestrophin 3. |
| 偶联标记 | Un-conjugated |
| 別名 | VMD2L3; Bestrophin-3; Vitelliform macular dystrophy 2-like protein 3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Best3 |
| 全名 | bestrophin 3 |
| 背景介绍 | BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. [UniProt] |
| 预测分子量 | 76 kDa |
检测图片 (1)
ARG10775 anti-Bestrophin 3 antibody IHC-P image
Immunohistochemistry: PFA-fixed and paraffin-embedded Mouse glomerulus stained with ARG10775 anti-Bestrophin 3 antibody at 1:100 dilution. Incubation for 36 h at 4°C. Requires antigen retrieval.
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