anti-beta 2 Microglobulin antibody [B2M-01] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [B2M-01] recognizes beta 2 Microglobulin
  • 反应物种: Hu
  • 不反应物种: Ms, Bov, Chk, Dog, Rb
  • 应用: FACS
  • 特异性: The clone B2M-01 reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes._x000D_
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: B2M-01
  • 同位型: IgG2a
  • Brand:
CAT.NO. : ARG62677
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [B2M-01] recognizes beta 2 Microglobulin
反应物种Hu
不反应物种Ms, Bov, Chk, Dog, Rb
应用FACS
特异性The clone B2M-01 reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes._x000D_
宿主Mouse
克隆Monoclonal
克隆号B2M-01
同位型IgG2a
靶点名称beta 2 Microglobulin
抗原物种Human
抗原Purified human beta2-microglobulin
偶联标记FITC
別名Beta-2-microglobulin
应用说明
应用建议
应用推荐稀释比
FACS1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化说明The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC.
缓冲液PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂15 mM Sodium azide
浓度1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 567 Human B2M

Swiss-port # P61769 Human Beta-2-microglobulin

基因名称B2M
全名beta-2-microglobulin
背景介绍Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
生物功能Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody
预测分子量14 kDa
翻译后修饰Glycation of Ile-21 is observed in long-term hemodialysis patients.
检测图片 (1)
  • ARG62677 anti-beta 2 Microglobulin antibody [B2M-01] (FITC) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG62677 anti-beta 2 Microglobulin antibody [B2M-01] (FITC).

参考文献

克隆号文献

Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking.

Tiwari S et al.
J Cell Sci.,  (2011)

publication_link

 

hr_line

FcRn binding properties of an abnormal truncated analbuminemic albumin variant.

ELISA / Human

Andersen JT et al.
Clin Biochem.,  (2010)

publication_link

 

hr_line

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

WB / Human

Slany A et al.
J Proteome Res.,  (2010)

publication_link

 

hr_line

Oncostatin M enhances the antiviral effects of type I interferon and activates immunostimulatory functions in liver epithelial cells.

WB / Human

Larrea E et al.
J Virol.,  (2009)

publication_link

 

hr_line

Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies.

Wilson AM et al.
Circulation.,  (2007)

publication_link

 

hr_line

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types.

Kanda Y et al.
Glycobiology.,  (2007)

publication_link

 

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