anti-beta 2 Microglobulin antibody [B2M-02] (Biotin)
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CAT.NO. : ARG62679
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Product Details
概述
| 产品描述 | Biotin-conjugated Mouse Monoclonal antibody [B2M-02] recognizes beta 2 Microglobulin |
|---|---|
| 反应物种 | Hu, Pig |
| 应用 | FACS |
| 特异性 | The clone B2M-02 reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes._x000D_ |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B2M-02 |
| 同位型 | IgG1 |
| 靶点名称 | beta 2 Microglobulin |
| 抗原物种 | Human |
| 抗原 | Purified isolated human beta2-microglobulin. |
| 偶联标记 | Biotin |
| 別名 | Beta-2-microglobulin |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | B2M |
| 全名 | beta-2-microglobulin |
| 背景介绍 | Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. |
| 生物功能 | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Glycation of Ile-21 is observed in long-term hemodialysis patients. |
检测图片 (2)
ARG62679 anti-beta 2 Microglobulin antibody [B2M-02] (Biotin) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG62679 anti-beta 2 Microglobulin antibody [B2M-02] (Biotin), followed by Streptavidin (APC).
ARG62679 anti-beta 2 Microglobulin antibody [B2M-02] (Biotin) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG62679 anti-beta 2 Microglobulin antibody [B2M-02] (Biotin).
参考文献
克隆号文献
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin.
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