anti-beta 2 Microglobulin antibody [BBM.1]
CAT.NO. : ARG56072
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概述
| 产品描述 | Mouse Monoclonal antibody [BBM.1] recognizes beta 2 Microglobulin |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-Fr, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | BBM.1 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | beta 2 Microglobulin |
| 抗原物种 | Human |
| 抗原 | MOLT-4 Human T cell line. |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-2-microglobulin |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Raji | ||||||||||
| 实际分子量 | ~ 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | B2M |
| 全名 | beta-2-microglobulin |
| 背景介绍 | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014] |
| 生物功能 | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
| 细胞定位 | Cytoplasmic |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Glycation of Ile-21 is observed in long-term hemodialysis patients. |
检测图片 (3)
ARG56072 anti-beta 2 Microglobulin antibody [BBM.1] ICC/IF image
Immunofluorescence: Permeabilized HeLa cells stained with ARG56072 anti-beta 2 Microglobulin antibody [BBM.1] (green). Reddot (red) for nuclear staining.
ARG56072 anti-beta 2 Microglobulin antibody [BBM.1] WB image
Western blot: Raji cell lysate stained with ARG56072 anti-beta 2 Microglobulin antibody [BBM.1].
ARG56072 anti-beta 2 Microglobulin antibody [BBM.1] FACS image
Flow Cytometry: PFA-fixed HeLa cells stained with ARG56072 anti-beta 2 Microglobulin antibody [BBM.1] (blue); Isotype control (red).
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