anti-Biglycan antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes Biglycan
  • 反应物种: Hu, Ms
  • 预测物种: Dog, Rat
  • 应用: ICC/IF
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Biglycan
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64083
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes Biglycan
反应物种Hu, Ms
预测物种Dog, Rat
应用ICC/IF
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称Biglycan
抗原物种Human
抗原C-DRLAIQFGNYKK (C-terminal)
偶联标记Un-conjugated
別名Biglycan; Bone/cartilage proteoglycan I; SLRR1A; PGI; DSPG1; PG-S1
应用说明
应用建议
应用推荐稀释比
ICC/IF10 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12111 Mouse BGN

GeneID: 633 Human BGN

Swiss-port # P21810 Human Biglycan

Swiss-port # P28653 Mouse Biglycan

背景介绍The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009]
研究领域Developmental Biology antibody; Signaling Transduction antibody
预测分子量42 kDa
翻译后修饰The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
检测图片 (2)
  • ARG64083 anti-Biglycan antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed NIH/3T3 cells permeabilized with 0.15% Triton. Cells were stained with ARG64083 anti-Biglycan antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.

  • ARG64083 anti-Biglycan antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed HepG2 cells permeabilized with 0.15% Triton. Cells were stained with ARG64083 anti-Biglycan antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.

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