anti-BiP / GRP78 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes BiP / GRP78
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: BiP / GRP78
  • 抗原物种: Human
  • 抗原: Synthetic peptide within aa. 550-650 of Human BiP / GRP78 (NP_005338.1).
  • Brand:
CAT.NO. : ARG40549
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes BiP / GRP78
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称BiP / GRP78
抗原物种Human
抗原Synthetic peptide within aa. 550-650 of Human BiP / GRP78 (NP_005338.1).
偶联标记Un-conjugated
別名Heat shock 70 kDa protein 5; BiP; GRP-78; Endoplasmic reticulum lumenal Ca; MIF2; 78 kDa glucose-regulated protein; GRP78; Immunoglobulin heavy chain-binding protein; HEL-S-89n; BIP; 2+
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HT-1080
实际分子量78 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14828 Mouse HSPA5

GeneID: 25617 Rat HSPA5

GeneID: 3309 Human HSPA5

基因名称HSPA5
全名heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
背景介绍The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010]
生物功能Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. [UniProt]
细胞定位Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt]
研究领域Controls and Markers antibody; ER Marker antibody; Endoplasmic reticulum antibody
预测分子量72 kDa
检测图片 (2)
  • ARG40549 anti-BiP / GRP78 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG40549 anti-BiP / GRP78 antibody at 1:100 dilution.

  • ARG40549 anti-BiP / GRP78 antibody WB image

    Western blot: 25 µg of HT-1080 cell lysate stained with ARG40549 anti-BiP / GRP78 antibody at 1:1000 dilution.

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