anti-BMP1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes BMP1
  • 反应物种: Hu
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: BMP1
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human BMP1.
  • Brand:
CAT.NO. : ARG42078
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes BMP1
反应物种Hu
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称BMP1
抗原物种Human
抗原Recombinant protein of Human BMP1.
偶联标记Un-conjugated
別名OI13; Procollagen C-proteinase; PCP; PCOLC; PCP2; BMP-1; Bone morphogenetic protein 1; Mammalian tolloid protein; TLD; EC 3.4.24.19; mTld
应用说明
应用建议
应用推荐稀释比
ICC/IF1:25
WB1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U-251 MG
实际分子量~ 95 kDa
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide.
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 649 Human BMP1

Swiss-port # P13497 Human Bone morphogenetic protein 1

基因名称BMP1
全名bone morphogenetic protein 1
背景介绍This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
生物功能Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX. [UniProt]
细胞定位Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Note=Co-localizes with POSTN in the Golgi. [UniProt]
预测分子量111 kDa
翻译后修饰Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion. [UniProt]
检测图片 (2)
  • ARG42078 anti-BMP1 antibody ICC/IF image

    Immunofluorescence: 4% Paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized A549 cells stained with ARG42078 anti-BMP1 antibody (green) at 1:25 dilution. Dylight® 554 Phalloidin (red) for cytoplasmic actin staining. DAPI (blue) for nuclear staining.

  • ARG42078 anti-BMP1 antibody WB image

    Western blot: 20 µg of U-251 MG whole cell lysate stained with ARG42078 anti-BMP1 antibody at 1:2000 dilution.

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