anti-BMP7 antibody [4E7]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [4E7] recognizes BMP7
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 4E7
  • 同位型: IgG1, kappa
  • 靶点名称: BMP7
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56924
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Product Details
概述
产品描述Mouse Monoclonal antibody [4E7] recognizes BMP7
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Mouse
克隆Monoclonal
克隆号4E7
同位型IgG1, kappa
靶点名称BMP7
抗原物种Human
抗原Recombinant fragment around aa. 293-431 of Human BMP7.
偶联标记Un-conjugated
別名BMP-7; OP-1; Osteogenic protein 1; Eptotermin alfa; Bone morphogenetic protein 7
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12162 Mouse BMP7

GeneID: 655 Human BMP7

Swiss-port # P18075 Human Bone morphogenetic protein 7

Swiss-port # P23359 Mouse Bone morphogenetic protein 7

基因名称BMP7
全名bone morphogenetic protein 7
背景介绍The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
生物功能Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. [UniProt]
预测分子量49 kDa
翻译后修饰Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms.
检测图片 (3)
  • ARG56924 anti-BMP7 antibody [4E7] ICC/IF image

    Immunoflorescense: HeLa cell line stained with ARG56924 anti-BMP7 antibody [4E7] at 1:100 (Green).

    DAPI (Blue) for nucleus staining.

  • ARG56924 anti-BMP7 antibody [4E7] WB image

    Western blot: 40 µg of Mouse brain tissue lysates stained with ARG56924 anti-BMP7 antibody [4E7] at 1:1000.

  • ARG56924 anti-BMP7 antibody [4E7] WB image

    Western blot: Mouse kidney (MK) and Rat heart (RH) stained with ARG56924 anti-BMP7 antibody [4E7] at 1:1000.

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