anti-BMP9 antibody
CAT.NO. : ARG59620
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes BMP9 |
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反应物种 | Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | BMP9 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 320-429 of Human BMP9 (NP_057288.1). |
偶联标记 | Un-conjugated |
別名 | GDF-2; BMP-9; Growth/differentiation factor 2; BMP9; Bone morphogenetic protein 9; HHT5 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Rat skeletal muscle and Mouse skeletal muscle | ||||
实际分子量 | 47 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | GDF2 |
全名 | growth differentiation factor 2 |
背景介绍 | The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jan 2014] |
生物功能 | Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. [UniProt] |
细胞定位 | Secreted. [UniProt] |
预测分子量 | 47 kDa |
