anti-BMPER / Crossveinless 2 antibody
CAT.NO. : ARG42660
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BMPER / Crossveinless 2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Hrs, Pig, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BMPER / Crossveinless 2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminal region of Human BMPER / Crossveinless 2. (Within the following region: NGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTV) |
| 偶联标记 | Un-conjugated |
| 別名 | hCV2; CV-2; CV2; BMP-binding endothelial regulator protein; Protein crossveinless-2; CRIM3; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator |
应用说明
| 预测反应性说明 | Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea pig: 93%; Horse: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 79% | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
| ||||||
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human fetal heart |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8N8U9 Human BMP-binding endothelial regulator protein |
|---|---|
| 基因名称 | BMPER |
| 全名 | BMP binding endothelial regulator |
| 背景介绍 | This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011] |
| 生物功能 | Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 76 kDa |
检测图片 (2)
ARG42660 anti-BMPER / Crossveinless 2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung (respiratory epethelium tissue) stained with ARG42660 anti-BMPER / Crossveinless 2 antibody at 5 µg/ml dilution.
ARG42660 anti-BMPER / Crossveinless 2 antibody WB image
Western blot: Human fetal heart lysate stained with ARG42660 anti-BMPER / Crossveinless 2 antibody at 1 µg/ml dilution.
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