anti-BPGM antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG57358
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BPGM |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BPGM |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human BPGM. |
| 偶联标记 | Un-conjugated |
| 別名 | 2,3-diphosphoglycerate mutase; BPGM; Bisphosphoglycerate mutase; DPGM; EC 5.4.2.11; 2,3-bisphosphoglycerate synthase; EC 5.4.2.4; BPG-dependent PGAM; EC 3.1.3.13; 2,3-bisphosphoglycerate mutase, erythrocyte |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse spleen |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BPGM |
| 全名 | 2,3-bisphosphoglycerate mutase |
| 背景介绍 | 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009] |
| 生物功能 | Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities. [UniProt] |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | Glycation of Lys-159 in diabetic patients inactivates the enzyme. |
检测图片 (1)
ARG57358 anti-BPGM antibody WB image
Western blot: Mouse spleen lysate stained with ARG57358 anti-BPGM antibody.
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