anti-BRWD1 / WDR9 antibody
CAT.NO. : ARG57407
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概述
产品描述 | Rabbit Polyclonal antibody recognizes BRWD1 / WDR9 |
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反应物种 | Hu, Ms |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | BRWD1 / WDR9 |
抗原物种 | Human |
抗原 | Recombinant Protein of Human BRWD1 / WDR9. |
偶联标记 | Un-conjugated |
別名 | N143; WD repeat-containing protein 9; C21orf107; WDR9; Bromodomain and WD repeat-containing protein 1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | HeLa |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q921C3 Mouse Bromodomain and WD repeat-containing protein 1 Swiss-port # Q9NSI6 Human Bromodomain and WD repeat-containing protein 1 |
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基因名称 | BRWD1 |
全名 | bromodomain and WD repeat domain containing 1 |
背景介绍 | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011] |
生物功能 | May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. [UniProt] |
预测分子量 | 263 kDa |
