anti-CACNA1H antibody [N55/10]

CAT.NO. : ARG24119

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [N55/10] recognizes CACNA1H
反应物种	Hu, Ms, Rat
应用	ICC/IF, IHC-Fr, IHC-P, IP, WB
特异性	No cross-reactivity against Cav1.3.
宿主	Mouse
克隆	Monoclonal
克隆号	N55/10
同位型	IgG1
靶点名称	CACNA1H
抗原物种	Human
抗原	Human fusion protein of CACNA1H
偶联标记	Un-conjugated
Protein Full name	Voltage-dependent T-type calcium channel subunit alpha-1H
別名	CACNA1H; Calcium Voltage-Gated Channel Subunit Alpha1 H; Calcium Channel, Voltage-Dependent, T Type, Alpha 1H Subunit; Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1H; Low-Voltage-Activated Calcium Channel Alpha1 3.2 Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav3.2; Cav3.2; Calcium Channel, Voltage-Dependent, T Type, Alpha 1Hb Subunit; Voltage Dependent T-Type Calcium Channel Alpha-1H Subunit; Low-Voltage-Activated Calcium Channel Alpha13.2 Subunit; Voltage-Gated Calcium Channel Alpha Subunit Cav3.2; Voltage-Gated Calcium Channel Alpha Subunit CavT.2; CACNA1HB; CAV3.2; HALD4; ECA6; EIG6

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide
抗菌剂	0.09% Sodium azide
稳定剂	50% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 114862 Rat CACNA1H GeneID: 8912 Human CACNA1H Swiss-port # O95180 Human Voltage-dependent T-type calcium channel subunit alpha-1H Swiss-port # Q9EQ60 Rat Voltage-dependent T-type calcium channel subunit alpha-1H
全名	Calcium Voltage-Gated Channel Subunit Alpha1 H
背景介绍	This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).
生物功能	Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation.
细胞定位	Cell membrane, Membrane
预测分子量	261 kDa
翻译后修饰	Glycoprotein

检测图片 (4)

ARG24119 anti-CACNA1H antibody [N55/10] IHC-P image
Immunohistochemistry: Human hippocampus stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
ARG24119 anti-CACNA1H antibody [N55/10] IHC-Fr image
Immunohistochemistry: Human hippocampus stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
ARG24119 anti-CACNA1H antibody [N55/10] ICC/IF image
Immunofluorescence: SH-SY5Y stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.
ARG24119 anti-CACNA1H antibody [N55/10] WB image
Western blot: Rat brain stained with ARG24119 anti-CACNA1H antibody [N55/10] at 1:1000 dilution.

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