anti-CACNG3 antibody
CAT.NO. : ARG66570
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概述
产品描述 | Rabbit Polyclonal antibody recognizes CACNG3 |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CACNG3 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human CACNG3. |
偶联标记 | Un-conjugated |
別名 | TARP gamma-3; Transmembrane AMPAR regulatory protein gamma-3; Voltage-dependent calcium channel gamma-3 subunit; Neuronal voltage-gated calcium channel gamma-3 subunit |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
实际分子量 | 34 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CACNG3 |
全名 | calcium channel, voltage-dependent, gamma subunit 3 |
背景介绍 | The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010] |
生物功能 | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). [UniProt] |
细胞定位 | Membrane; Multi-pass membrane protein. Note=Displays a somatodendritic localization and is excluded from axons in neurons. [UniProt] |
预测分子量 | 36 kDa |
