anti-Calcitonin Receptor antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG56226
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Calcitonin Receptor |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Calcitonin Receptor |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 445-474 (C-terminus) of Human Calcitonin Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | CT-R; CTR1; CTR; CRT; Calcitonin receptor |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CALCR |
| 全名 | calcitonin receptor |
| 背景介绍 | This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| 生物功能 | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 预测分子量 | 55 kDa |
检测图片 (3)
ARG56226 anti-Calcitonin Receptor antibody ICC/IF image
Immunofluorescence: MCF7 cells stained with ARG56226 anti-Calcitonin Receptor antibody (green). DAPI (blue) for nuclear staining.
ARG56226 anti-Calcitonin Receptor antibody WB image
Western blot: 35 µg of MCF7 cell lysate stained with ARG56226 anti-Calcitonin Receptor antibody at 1:1000 dilution with (+) or without (-) blocking peptides.
ARG56226 anti-Calcitonin Receptor antibody FACS image
Flow Cytometry: HL-60 cells stained with ARG56226 anti-Calcitonin Receptor antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
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