anti-Calpain S1 antibody [1D11]

CAT.NO. : ARG57147

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1D11] recognizes Calpain S1
反应物种	Hu
应用	FACS, ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	1D11
同位型	IgG1, kappa
靶点名称	Calpain S1
抗原物种	Human
抗原	Recombinant fragment around aa. 84-268 of Human Calpain S1
偶联标记	Un-conjugated
別名	CANPS; Calcium-dependent protease small subunit; CSS1; Calpain regulatory subunit; CALPAIN4; CDPS; CAPN4; Calcium-dependent protease small subunit 1; CANP small subunit; CANP; Calcium-activated neutral proteinase small subunit; Calpain small subunit 1

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 826 Human CAPNS1 Swiss-port # P04632 Human Calpain small subunit 1
基因名称	CAPNS1
全名	calpain, small subunit 1
背景介绍	This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
生物功能	Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. [UniProt]
预测分子量	28 kDa

检测图片 (3)

ARG57147 anti-Calpain S1 antibody [1D11] ICC/IF image
Immunofluorescence: HeLa cells line stained with ARG57147 anti-Calpain S1 antibody [1D11] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57147 anti-Calpain S1 antibody [1D11] FACS image
Flow Cytometry: HeLa cell line stained with ARG57147 anti-Calpain S1 antibody [1D11] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody: Mouse IgG (black line).
ARG57147 anti-Calpain S1 antibody [1D11] WB image
Western blot: 50 ng of 1) CAPNS1 recombinant proteins, 40 µg of 2) HeLa, 3) A431, 4) 293T, 5) Balb/3T3, and 6) U87MG cell lysates stained with ARG57147 anti-Calpain S1 antibody [1D11] at 1:1000.

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