anti-Calponin 1 antibody [CALP]
CAT.NO. : ARG62380
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概述
产品描述 | Mouse Monoclonal antibody [CALP] recognizes Calponin 1 |
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反应物种 | Hu, Rat |
应用 | FACS, ICC/IF, IHC-Fr, IHC-P |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | CALP |
同位型 | IgG1 |
靶点名称 | Calponin 1 |
抗原物种 | Human |
抗原 | Crude human uterus extract |
偶联标记 | Un-conjugated |
別名 | Calponin H1, smooth muscle; Sm-Calp; HEL-S-14; SMCC; Calponin-1; Basic calponin |
应用说明
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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阳性对照 | Myoepithelium in normal breast glands. |
属性
形式 | Liquid |
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纯化 | Protein G purified |
缓冲液 | 10mM PBS (pH 7.4), 0.2% BSA and 0.09% Sodium azide |
抗菌剂 | 0.09% Sodium azide |
稳定剂 | 0.2% BSA |
浓度 | 0.2 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CNN1 |
全名 | calponin 1, basic, smooth muscle |
背景介绍 | Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. |
生物功能 | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody |
预测分子量 | 33 kDa |
参考文献
克隆号文献
