anti-Calponin 1 antibody [CALP]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [CALP] recognizes Calponin 1
  • 反应物种: Hu, Rat
  • 应用: FACS, ICC/IF, IHC-Fr, IHC-P
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: CALP
  • 同位型: IgG1
  • 靶点名称: Calponin 1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG62380
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Product Details
概述
产品描述Mouse Monoclonal antibody [CALP] recognizes Calponin 1
反应物种Hu, Rat
应用FACS, ICC/IF, IHC-Fr, IHC-P
宿主Mouse
克隆Monoclonal
克隆号CALP
同位型IgG1
靶点名称Calponin 1
抗原物种Human
抗原Crude human uterus extract
偶联标记Un-conjugated
別名Calponin H1, smooth muscle; Sm-Calp; HEL-S-14; SMCC; Calponin-1; Basic calponin
应用说明
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Myoepithelium in normal breast glands.
属性
形式Liquid
纯化Protein G purified
缓冲液10mM PBS (pH 7.4), 0.2% BSA and 0.09% Sodium azide
抗菌剂0.09% Sodium azide
稳定剂0.2% BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1264 Human CNN1

GeneID: 65204 Rat CNN1

Swiss-port # P51911 Human Calponin-1

Swiss-port # Q08290 Rat Calponin-1

基因名称CNN1
全名calponin 1, basic, smooth muscle
背景介绍Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions.
生物功能Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). [UniProt]
研究领域Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody
预测分子量33 kDa
参考文献

克隆号文献

Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries.

ICC/IF / Human

Harhun MI et al.
J Cell Mol Med.,  (2012)

publication_link

 

hr_line

Pericardial synovial sarcoma, a potential for misdiagnosis: clinicopathologic and molecular cytogenetic analysis of three cases with literature review.

IHC / Human

Cheng Y et al.
Am J Clin Pathol.,  (2012)

publication_link

 

hr_line

Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma.

IHC-P / Human

Hua X et al.
Diagn Pathol.,  (2011)

publication_link

 

hr_line

Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement.

IHC / Human

Borak S et al.
Diagn Cytopathol.,  (2012)

publication_link

 

hr_line

Artificial niche combining elastomeric substrate and platelets guides vascular differentiation of bone marrow mononuclear cells.

WB, IHC-Fr / Rat

Wu W et al.
Tissue Eng Part A.,  (2011)

publication_link

 

hr_line

Explant outgrowth, propagation and characterization of human pericytes.

ICC/IF, FACS / Human

Maier CL et al.
Microcirculation.,  (2010)

publication_link

 

hr_line

Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffold.

IHC-FoFr / Rat

Hashizume R et al.
Biomaterials.,  (2010)

publication_link

 

hr_line

Interstitial cells from rat middle cerebral artery belong to smooth muscle cell type.

ICC/IF / Rat

Harhun MI et al.
J Cell Mol Med.,  (2009)

publication_link

 

hr_line

Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment.

WB / Rat

Liu CG et al.
Cancer Res.,  (2005)

publication_link

 

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