anti-CaMKII phospho (Thr286) antibody
CAT.NO. : ARG51767
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CaMKII phospho (Thr286) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CaMKII |
| 抗原物种 | Human |
| 抗原 | Peptide sequence around phosphorylation site of threonine 286 (Q-E-T(p)-V-D) derived from Human CaMKII. |
| 偶联标记 | Un-conjugated |
| 別名 | CAMKA; CaMK-II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; EC 2.7.11.17 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 缓冲液 | PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CAMK2A |
| 全名 | calcium/calmodulin-dependent protein kinase II alpha |
| 背景介绍 | CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. |
| 生物功能 | CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). [UniProt] |
| 产品亮点 | Related Antibody Duos and Panels: ARG30157 Phospho CaMKII Antibody Duo Related products: CaMKII antibodies; CaMKII Duos / Panels; Anti-Rabbit IgG secondary antibodies; |
| 研究领域 | Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 54 kDa |
检测图片 (2)
ARG51767 anti-CaMKII phospho (Thr286) antibody WB image
Western blot: Extracts from 293 cells untreated or treated with PMA stained with ARG51767 anti-CaMKII phospho (Thr286) antibody.
ARG51767 anti-CaMKII phospho (Thr286) antibody WB image
Western blot: Extracts from Rat brain tissue treated with Lambda Phosphotase or calf intestinal phosphatase (CIP),stained with ARG51767 anti-CaMKII phospho (Thr286) antibody.
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