anti-CAPZB antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CAPZB
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CAPZB
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human CAPZB
  • Brand:
CAT.NO. : ARG55298
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CAPZB
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CAPZB
抗原物种Human
抗原Recombinant protein of Human CAPZB
偶联标记Un-conjugated
別名CapZ beta; F-actin-capping protein subunit beta; CAPZ; CAPB; CAPPB
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat small intestine, Mouse spleen and A431
实际分子量~ 31 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12345 Mouse CAPZB

GeneID: 298584 Rat CAPZB

GeneID: 832 Human CAPZB

基因名称CAPZB
全名capping protein (actin filament) muscle Z-line, beta
背景介绍This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Aug 2013]
生物功能F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. [UniProt]
研究领域Signaling Transduction antibody
预测分子量31 kDa
检测图片 (3)
  • ARG55298 anti-CAPZB antibody ICC/IF image

    Immunofluorescence: U2OS cells stained with ARG55298 anti-CAPZB antibody at 1:100 dilution.

  • ARG55298 anti-CAPZB antibody WB image

    Western blot: 25 µg of A431 cell lysate stained with ARG55298 anti-CAPZB antibody at 1:1000 dilution.

  • ARG55298 anti-CAPZB antibody WB image

    Western blot: 25 µg of Rat small intestine and Mouse spleen lysates stained with ARG55298 anti-CAPZB antibody at 1:1000 dilution.

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