anti-CARD9 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 偶联标记:
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Brand:
CAT.NO. : ARG44636
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CARD9 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | CARD9 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | CARD9; Caspase Recruitment Domain Family Member 9; Caspase Recruitment Domain-Containing Protein 9; HCARD9; Caspase Recruitment Domain Family, Member 9; CANDF2; IMD103 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9H257 Human Caspase recruitment domain-containing protein 9 |
|---|---|
| 基因名称 | CARD9 |
| 全名 | Caspase Recruitment Domain Family Member 9 |
| 背景介绍 | The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008] |
| 生物功能 | In response to L.monocytogenes infection, required for the production of inflammatory cytokines activated by intracellular peptidoglycan: acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 62 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (2)
ARG44636 anti-CARD9 antibody WB image
Western blot: THP1 stained with ARG44636 anti-CARD9 antibody at 1 µg/mL dilution.
ARG44636 anti-CARD9 antibody IP image
Immunoprecipitation: THP1 lysate immunoprecipitated with 2.5 µg of ARG44636 anti-CARD9 antibody.
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