anti-Caspase 2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41624
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Caspase 2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Caspase 2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Caspase 2. |
| 偶联标记 | Un-conjugated |
| 別名 | Protease ICH-1; PPP1R57; NEDD-2; EC 3.4.22.55; NEDD2; Caspase-2; CASP-2; ICH1; Neural precursor cell expressed developmentally down-regulated protein 2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | ~ 48 kDa (uncleaved); ~ 32 kDa (cleaved) |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CASP2 |
| 全名 | caspase 2, apoptosis-related cysteine peptidase |
| 背景介绍 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| 生物功能 | Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [UniProt] |
| 预测分子量 | 51 kDa (uncleaved) |
| 翻译后修饰 | The mature protease can process its own propeptide, but not that of other caspases. [UniProt] |
检测图片 (1)
ARG41624 anti-Caspase 2 antibody WB image
Western blot: HeLa cell lysate stained with ARG41624 anti-Caspase 2 antibody.
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