anti-Cathelicidin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG54943
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cathelicidin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, ICC/IF, IHC, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cathelicidin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (17 aa) within aa. 50-100 of Human Cathelicidin. |
| 偶联标记 | Un-conjugated |
| 別名 | FALL39; CRAMP; HSD26; CAP18; 18 kDa cationic antimicrobial protein; FALL-39 peptide antibiotic; LL37; FALL-39; CAP-18; Cathelicidin antimicrobial peptide; hCAP-18 |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Human Spleen Tissue Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P49913 Human Cathelicidin antimicrobial peptide |
|---|---|
| 基因名称 | CAMP |
| 全名 | cathelicidin antimicrobial peptide |
| 背景介绍 | Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response. |
| 生物功能 | Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. [UniProt] |
| 细胞定位 | Secreted |
| 研究领域 | Immune System antibody; Microbiology and Infectious Disease antibody |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | The N-terminus is blocked. |
检测图片 (3)
ARG54943 anti-Cathelicidin antibody WB image
Western blot: Human spleen tissue lysate stained with ARG54943 anti-Cathelicidin antibody at 1 μg/ml dilution.
ARG54943 anti-Cathelicidin antibody IHC image
Immunohistochemistry: Human spleen tissue stained with ARG54943 anti-Cathelicidin antibody at 5 μg/ml dilution.
ARG54943 anti-Cathelicidin antibody ICC/IF image
Immunofluorescence: Human Spleen cells stained with ARG54943 anti-Cathelicidin antibody at 20 μg/ml dilution.
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