anti-CBX3 / HP1 gamma antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes CBX3 / HP1 gamma
  • 反应物种: Hu, Ms
  • 预测物种: Dog, Rat
  • 应用: IHC-P, WB
  • 特异性: No cross-reactivity expected with HP1-alpha and HP1-beta. NP_009207.2 and NP_057671.2 represent same protein.
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CBX3 / HP1 gamma
  • Brand:
CAT.NO. : ARG63843
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes CBX3 / HP1 gamma
反应物种Hu, Ms
预测物种Dog, Rat
应用IHC-P, WB
特异性No cross-reactivity expected with HP1-alpha and HP1-beta. NP_009207.2 and NP_057671.2 represent same protein.
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称CBX3 / HP1 gamma
抗原物种Human
抗原C-EAFLNSQKAGKEKD
偶联标记Un-conjugated
別名HP1-GAMMA; Chromobox protein homolog 3; HP1Hs-gamma; HP1 gamma; HECH; Heterochromatin protein 1 homolog gamma; Modifier 2 protein
应用说明
应用建议
应用推荐稀释比
IHC-P2 - 3 µg/ml
WB0.3 - 1.0 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11335 Human CBX3

Swiss-port # Q13185 Human Chromobox protein homolog 3

背景介绍At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
产品亮点Related products:
CBX3 antibodies; CBX3 Duos / Panels; Anti-Goat IgG secondary antibodies;
Related news:
Senescence Marker Antibody Panel is launched
研究领域Gene Regulation antibody
预测分子量21 kDa
翻译后修饰Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.
检测图片 (2)
  • ARG63843 anti-CBX3 / HP1 gamma antibody WB image

    Western blot: A431 lysate (35 µg protein in RIPA buffer) stained with ARG63843 anti-CBX3 / HP1 gamma antibody at 0.3 µg/ml dilution.

  • ARG63843 anti-CBX3 / HP1 gamma antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Placenta. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63843 anti-CBX3 / HP1 gamma antibody at 2.5 µg/ml dilution followed by AP-staining.

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