anti-CCL2 / MCP1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes CCL2 / MCP1 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, IHC, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL2 / MCP1 |
| 抗原物种 | Mouse |
| 抗原 | E. coli derived recombinant Mouse CCL2 / MCP1. |
| 偶联标记 | Un-conjugated |
| 別名 | MCP1; AI323594; MCAF; Monocyte chemotactic protein 1; Sigje; Small-inducible cytokine A2; Platelet-derived growth factor-inducible protein JE; HC11; SMC-CF; JE; Scya2; C-C motif chemokine 2; Monocyte chemoattractant protein 1; MCP-1 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
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| 基因名称 | Ccl2 |
| 全名 | chemokine (C-C motif) ligand 2 |
| 背景介绍 | This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015] |
| 生物功能 | Chemotactic factor that attracts monocytes, but not neutrophils. [UniProt] |
| 产品亮点 | Related products: MCP1 antibodies; MCP1 ELISA Kits; MCP1 Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. |
ARG56551 anti-CCL2 / MCP1 antibody IHC image
Immunohistochemistry: This antibody stained colchicine injected Mouse brain (including caudate putamen) tissue. The primary antibody ARG56551 anti-CCL2 / MCP1 antibody was incubated at 1.0 µg/ml overnight at 4˚C. This was followed by a peroxidase conjugated secondary antibody and then a fluorescein Tyramide Signal Amplification reagent.
ARG56551 anti-CCL2 / MCP1 antibody WB image
Western blot: 250 - 0.24 ng (left to right) of recombinant Mouse MCP-1 stained with ARG56551 anti-CCL2 / MCP1 antibody. (Under non-reducing conditions)
ARG56551 anti-CCL2 / MCP1 antibody standard curve image
ARG56551 anti-CCL2 / MCP1 antibody results of a typical standard run with optical density reading at 405 - 650 nm.
ARG56551 anti-CCL2 / MCP1 antibody WB image
Western blot: 250 - 0.24 ng (left to right) of recombinant Mouse MCP-1 stained with ARG56551 anti-CCL2 / MCP1 antibody. (Under reducing conditions)
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WB /
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