anti-CCL3 / MIP1 alpha antibody [1.2_3E8-2H6-2B6]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [1.2_3E8-2H6-2B6] recognizes CCL3 / MIP1 alpha
  • 反应物种: Hu
  • 应用: ELISA, Neut, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 1.2_3E8-2H6-2B6
  • 同位型: IgG1, kappa
  • 靶点名称: CCL3 / MIP1 alpha
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56596
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Product Details
概述
产品描述Mouse Monoclonal antibody [1.2_3E8-2H6-2B6] recognizes CCL3 / MIP1 alpha
反应物种Hu
应用ELISA, Neut, WB
宿主Mouse
克隆Monoclonal
克隆号1.2_3E8-2H6-2B6
同位型IgG1, kappa
靶点名称CCL3 / MIP1 alpha
抗原物种Human
抗原E.coli derived Recombinant Human MIP-1α (CCL3).
(ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA)
偶联标记Un-conjugated
別名MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA
应用说明
应用建议
应用推荐稀释比
ELISASandwich: 2.0 - 4.0 µg/ml with ARG56761 as a detection antibody
Neut5.0 - 10.0 µg/ml (To yield [ND50] of the biological activity of Human MIP - 1α (100 ng/ml) )
WB2.0 - 4.0 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6348 Human CCL3

Swiss-port # P10147 Human C-C motif chemokine 3

基因名称CCL3
全名chemokine (C-C motif) ligand 3
背景介绍This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
生物功能Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [UniProt]
预测分子量10 kDa
翻译后修饰N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
检测图片 (1)
  • ARG56596 anti-CCL3 / MIP1 alpha antibody [1.2_3E8-2H6-2B6] standard curve image

    Sandwich ELISA: ARG56596 anti-CCL3 / MIP1 alpha antibody [1.2_3E8-2H6-2B6] as a capture antibody at 2.0 - 4.0 µg/ml combined with ARG56761 anti-MIP1 alpha / CCL3 antibody (Biotin) as a detection antibody at ~ 1.0 - 2.0 µg/ml. Results of a typical standard run with optical density.

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