anti-CCL4 / MIP1 beta antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CCL4 / MIP1 beta
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide corresponding to aa. 22-48 of Human CCL4.
  • Brand:
CAT.NO. : ARG55030
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CCL4 / MIP1 beta
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 22-48 of Human CCL4.
偶联标记Un-conjugated
別名C-C motif chemokine 4; MIP-1-beta; Act-2; Protein H400; Small-inducible cytokine A4; ACT2; MIP-1B; Macrophage inflammatory protein 1-beta; Immune activation protein 2; SIS-gamma; ACT-2; Mip1b; Scya4; AT744.1
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse bladder
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20303 Mouse CCL4

GeneID: 6351 Human CCL4

Swiss-port # P13236 Human C-C motif chemokine 4

Swiss-port # P14097 Mouse C-C motif chemokine 4

基因名称CCL4
全名chemokine (C-C motif) ligand 4
背景介绍The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]
生物功能Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt]
研究领域Immune System antibody
预测分子量10 kDa
检测图片 (2)
  • ARG55030 anti-CCL4 / MIP1 beta antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human prostate carcinoma stained with ARG55030 anti-CCL4 / MIP1 beta antibody.

  • ARG55030 anti-CCL4 / MIP1 beta antibody WB image

    Western blot: 15 µg of Mouse bladder lysate stained with ARG55030 anti-CCL4 / MIP1 beta antibody.

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