anti-CCL4 / MIP1 beta antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta
  • 反应物种: Ms
  • 应用: ELISA, Neut, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CCL4 / MIP1 beta
  • 抗原物种: Mouse
  • 抗原: E. coli derived recombinant Mouse CCL4 / MIP1 beta.(APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN)
  • Brand:
CAT.NO. : ARG66092
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta
反应物种Ms
应用ELISA, Neut, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CCL4 / MIP1 beta
抗原物种Mouse
抗原E. coli derived recombinant Mouse CCL4 / MIP1 beta.
(APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN)
偶联标记Un-conjugated
別名ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
应用说明
应用建议
应用推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG66093 as a detection antibody
Neut8.0 - 10.0 µg/ml (To yield [ND50] of the biological activity of Murine MIP-1β (100.0 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20303 Mouse CCL4

Swiss-port # P14097 Mouse C-C motif chemokine 4

基因名称Ccl4
全名chemokine (C-C motif) ligand 4
背景介绍The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]
生物功能Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt]
预测分子量10 kDa
检测图片 (3)
  • ARG66092 anti-CCL4 / MIP1 beta antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under non-reducing conditions.

  • ARG66092 anti-CCL4 / MIP1 beta antibody standard curve image

    Sandwich ELISA: ARG66092 anti-CCL4 / MIP1 beta antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66093 anti-CCL4 / MCP1 beta antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.

  • ARG66092 anti-CCL4 / MIP1 beta antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under reducing conditions.

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