anti-CCL8 / MCP2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG66047
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CCL8 / MCP2 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CCL8 / MCP2 |
| 抗原物种 | Mouse |
| 抗原 | E. coli derived recombinant Mouse CCL8 / MCP2. (GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP) |
| 偶联标记 | Un-conjugated |
| 別名 | SCYA10; MCP2; Small-inducible cytokine A8; 6-76; Monocyte chemotactic protein 2; HC14; SCYA8; C-C motif chemokine 8; MCP-2; Monocyte chemoattractant protein 2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014] |
| 生物功能 | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. [UniProt] |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
检测图片 (3)
ARG66047 anti-CCL8 / MCP2 antibody WB image
Western blot: 250 - 0.24 ng of Mouse MCP-2 stained with ARG66047 anti-CCL8 / MCP2 antibody, under non-reducing conditions.
ARG66047 anti-CCL8 / MCP2 antibody standard curve image
Sandwich ELISA: ARG66047 anti-CCL8 / MCP2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66048 anti-CCL8 / MCP2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
ARG66047 anti-CCL8 / MCP2 antibody WB image
Western blot: 250 - 0.24 ng of Mouse MCP-2 stained with ARG66047 anti-CCL8 / MCP2 antibody, under reducing conditions.
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