anti-CD102 / ICAM2 antibody [B-T1]
![anti-CD102 / ICAM2 antibody [B-T1]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
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CAT.NO. : ARG22900
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [B-T1] recognizes CD102 / ICAM2 Mouse anti Human CD102 antibody, clone B-T1 recognizes human Intercellular adhesion molecule 2, also known as CD102 or ICAM-2. CD102 is a 275 amino acid ~55-65 kDa single pass type-1 transmembrane glycoprotein containing two Ig-like C2-type domains.Mouse anti Human CD102 antibody, clone B-T1 inhibits cell adhesion (Xie et al. 1995)and T cell activation and also recognises soluble ICAM-2. |
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| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B-T1 |
| 同位型 | IgG1 |
| 靶点名称 | CD102 / ICAM2 |
| 抗原物种 | Human |
| 抗原 | ICAM-2 transfected CHO cells. |
| 偶联标记 | Un-conjugated |
| 別名 | CD102; CD antigen CD102; Intercellular adhesion molecule 2; ICAM-2 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by ion exchange chromatography. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ICAM2 |
| 全名 | intercellular adhesion molecule 2 |
| 背景介绍 | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [UniProt] |
| 预测分子量 | 31 kDa |
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