anti-CD102 / ICAM2 antibody [CBR-IC2/2] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [CBR-IC2/2] recognizes CD102 / ICAM2
反应物种: Hu
应用: FACS
特异性: The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
宿主: Mouse
克隆: Monoclonal
克隆号: CBR-IC2/2
同位型: IgG2a
靶点名称: CD102 / ICAM2

CAT.NO. : ARG42286

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [CBR-IC2/2] recognizes CD102 / ICAM2
反应物种	Hu
应用	FACS
特异性	The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
宿主	Mouse
克隆	Monoclonal
克隆号	CBR-IC2/2
同位型	IgG2a
靶点名称	CD102 / ICAM2
抗原物种	Human
抗原	Human CD102 cDNA transfected COS cells.
偶联标记	PE
別名	CD102; CD antigen CD102; Intercellular adhesion molecule 2; ICAM-2

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3384 Human ICAM2 Swiss-port # P13598 Human Intercellular adhesion molecule 2
基因名称	ICAM2
全名	intercellular adhesion molecule 2
背景介绍	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Co-localizes with RDX, EZR and MSN in microvilli. [UniProt]
预测分子量	31 kDa

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