anti-CD106 / VCAM1 antibody [M/K-2] (PE)

产品描述: PE-conjugated Rat Monoclonal antibody [M/K-2] recognizes CD106 / VCAM1
反应物种: Ms
应用: BL, FACS, IHC-Fr, WB
特异性: Mouse CD106. The clone MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent MW of ~100 kDa under reducing conditions and 92 kDa under non-reducing conditions.
宿主: Rat
克隆: Monoclonal
克隆号: M/K-2
同位型: IgG1, kappa
靶点名称: CD106 / VCAM1

CAT.NO. : ARG20804

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	PE-conjugated Rat Monoclonal antibody [M/K-2] recognizes CD106 / VCAM1
反应物种	Ms
应用	BL, FACS, IHC-Fr, WB
特异性	Mouse CD106. The clone MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent MW of ~100 kDa under reducing conditions and 92 kDa under non-reducing conditions.
宿主	Rat
克隆	Monoclonal
克隆号	M/K-2
同位型	IgG1, kappa
靶点名称	CD106 / VCAM1
抗原物种	Mouse
抗原	BALB/3T3 and +/+2.4 cells
偶联标记	PE
別名	CD106; INCAM-100; Vascular cell adhesion protein 1; VCAM-1; CD antigen CD106; V-CAM 1

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	PBS, 0.1% Sodium azide and Sucrose.
抗菌剂	0.1% Sodium azide
稳定剂	Sucrose
浓度	0.1 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 22329 Mouse VCAM1 Swiss-port # P29533 Mouse Vascular cell adhesion protein 1
基因名称	VCAM1
全名	vascular cell adhesion molecule 1
背景介绍	This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
生物功能	Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [UniProt]
预测分子量	81 kDa
翻译后修饰	Sialoglycoprotein.

检测图片 (1)

ARG20804 anti-CD106 / VCAM1 antibody [M/K-2] (PE) FACS image
Flow Cytometry: BALB/c Mouse bone marrow cells stained with ARG20804 anti-CD106 / VCAM1 antibody [M/K-2] (PE) and ARG63064 anti-Ly6G antibody [RB6-8C5] (FITC).

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