anti-CD134 / OX40 antibody [Ber-ACT35] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [Ber-ACT35] recognizes CD134 / OX40
反应物种: Hu, NHuPrm
应用: FACS
特异性: The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of CD134 (TNFRSF4, OX40), an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
宿主: Mouse
克隆: Monoclonal
克隆号: Ber-ACT35
同位型: IgG1, kappa
靶点名称: CD134 / OX40

CAT.NO. : ARG42336

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [Ber-ACT35] recognizes CD134 / OX40
反应物种	Hu, NHuPrm
应用	FACS
特异性	The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of CD134 (TNFRSF4, OX40), an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
宿主	Mouse
克隆	Monoclonal
克隆号	Ber-ACT35
同位型	IgG1, kappa
靶点名称	CD134 / OX40
抗原物种	Human
抗原	HTLV 1-transformed HUT-102 cells.
偶联标记	PE
別名	CD134; TAX transcriptionally-activated glycoprotein 1 receptor; TXGP1L; OX40L receptor; Tumor necrosis factor receptor superfamily member 4; OX40; CD antigen CD134; IMD16; ACT35 antigen; ACT35

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7293 Human TNFRSF4 Swiss-port # P43489 Human Tumor necrosis factor receptor superfamily member 4
基因名称	TNFRSF4
全名	tumor necrosis factor receptor superfamily, member 4
背景介绍	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
生物功能	Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	29 kDa

检测图片 (3)

ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) FACS image
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.
ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) FACS image
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension and ARG53800 anti-CD25 antibody [MEM-181] (APC) at 10 µl / 100 µl of peripheral whole blood.
ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) FACS image
Flow Cytometry: Separation of Human CD134 positive CD25 positive cells (red-filled) from CD134 negative CD25 negative cells (black-dashed). Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 µl / 10^6 cells in 100 µl of cell suspension.

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