anti-CD137 antibody [4B4-1] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [4B4-1] recognizes CD137
反应物种: Hu, NHuPrm
应用: FACS
特异性: The mouse monoclonal antibody 4B4-1 recognizes an extracellular conformational epitope on CD137, an approximately 40 kDa type I transmembrane protein of the TNFR family expressed mainly on activated T cells.
宿主: Mouse
克隆: Monoclonal
克隆号: 4B4-1
同位型: IgG1, kappa
靶点名称: CD137

CAT.NO. : ARG42273

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [4B4-1] recognizes CD137
反应物种	Hu, NHuPrm
应用	FACS
特异性	The mouse monoclonal antibody 4B4-1 recognizes an extracellular conformational epitope on CD137, an approximately 40 kDa type I transmembrane protein of the TNFR family expressed mainly on activated T cells.
宿主	Mouse
克隆	Monoclonal
克隆号	4B4-1
同位型	IgG1, kappa
靶点名称	CD137
抗原物种	Human
抗原	Recombinant Human CD137 ectodomain.
偶联标记	PE
別名	ILA; CD137; T-cell antigen 4-1BB homolog; CDw137; T-cell antigen ILA; 4-1BB; CD antigen CD137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3604 Human TNFRSF9 Swiss-port # Q07011 Human Tumor necrosis factor receptor superfamily member 9
基因名称	TNFRSF9
全名	tumor necrosis factor receptor superfamily, member 9
背景介绍	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
生物功能	Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	28 kDa

检测图片 (1)

ARG42273 anti-CD137 antibody [4B4-1] (PE) FACS image
Flow Cytometry: PHA activated PBMC stained with ARG42273 anti-CD137 antibody [4B4-1] (PE) and anti-CD25 antibody (APC).

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