anti-CD146 antibody [P1H12] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [P1H12] recognizes CD146
反应物种: Hu, Ms, Dog, Rb
不反应物种: Rat
应用: FACS
特异性: The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes.
宿主: Mouse
克隆: Monoclonal
克隆号: P1H12
同位型: IgG1

CAT.NO. : ARG42346

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Size:

50 tests

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [P1H12] recognizes CD146
反应物种	Hu, Ms, Dog, Rb
不反应物种	Rat
应用	FACS
特异性	The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes.
宿主	Mouse
克隆	Monoclonal
克隆号	P1H12
同位型	IgG1
靶点名称	CD146
抗原物种	Human
抗原	Cultured Human umbilical cells.
偶联标记	PE
別名	Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; Cell surface glycoprotein MUC18; Melanoma cell adhesion molecule; CD146; MUC18; CD antigen CD146; S-endo 1 endothelial-associated antigen

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4162 Human MCAM GeneID: 84004 Mouse MCAM Swiss-port # P43121 Human Cell surface glycoprotein MUC18 Swiss-port # Q8R2Y2 Mouse Cell surface glycoprotein MUC18
基因名称	MCAM
全名	melanoma cell adhesion molecule
生物功能	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. [UniProt]
细胞定位	Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	72 kDa

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