anti-CD154 / CD40L antibody [24-31] (APC)
![anti-CD154 / CD40L antibody [24-31] (APC)](/upload/image/products/ARG44244_210_205.jpg)
![anti-CD154 / CD40L antibody [24-31] (APC)](/upload/image/products/ARG44244.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG44244
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Product Details
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [24-31]recognizes CD154 / CD40L |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 24-31 |
| 同位型 | IgG1 |
| 靶点名称 | CD154 / CD40L |
| 抗原物种 | Human |
| 抗原 | Human CD154 fusion protein. |
| 偶联标记 | APC |
| 別名 | TNFSF5; IMD3; T-cell antigen Gp39; HIGM1; CD40-L; gp39; CD40 ligand; Tumor necrosis factor ligand superfamily member 5; CD40L; CD154; TRAP; CD antigen CD154; hCD40L; IGM; T-BAM; TNF-related activation protein |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Do not freeze. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD40LG |
| 全名 | CD40 ligand |
| 背景介绍 | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008] |
| 生物功能 | Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type II membrane protein. Cell surface. CD40 ligand, soluble form: Secreted. [UniProt] |
| 翻译后修饰 | The soluble form derives from the membrane form by proteolytic processing. N-linked glycan is a mixture of high mannose and complex type. Glycan structure does not influence binding affinity to CD40. Not O-glycosylated. [UniProt] |
检测图片 (1)
ARG44244 anti-CD154 / CD40L antibody [24-31] (APC) FACS image
Flow Cytometry: Human whole blood stained with ARG44244 anti-CD154 / CD40L antibody [24-31] (APC) at 10 μl/ 100 μl whole blood dilution.
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