anti-CD157 / BST1 antibody [SY11B5]
![anti-CD157 / BST1 antibody [SY11B5]](/upload/image/products/ARG65543_FACS_1_210_205.jpg)
![anti-CD157 / BST1 antibody [SY11B5]](/upload/image/products/ARG65543_FACS_1.jpg)
Key features and details
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- 应用:
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- 靶点名称:
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CAT.NO. : ARG65543
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [SY11B5] recognizes CD157 / BST1 |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | FACS, IHC-Fr, IP, WB |
| 特异性 | The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPIanchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SY11B5 |
| 同位型 | IgG1 |
| 靶点名称 | CD157 / BST1 |
| 抗原物种 | Human |
| 抗原 | Human CD157 |
| 偶联标记 | Un-conjugated |
| 別名 | cADPr hydrolase 2; ADP-ribosyl cyclase 2; Cyclic ADP-ribose hydrolase 2; BST-1; Bone marrow stromal antigen 1; CD157; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; CD antigen CD157; EC 3.2.2.6 |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from hybridoma culture supernatant by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q10588 Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
|---|---|
| 基因名称 | BST1 |
| 全名 | bone marrow stromal cell antigen 1 |
| 背景介绍 | CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates.CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role. |
| 生物功能 | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [UniProt] |
| 研究领域 | Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 36 kDa |
检测图片 (1)
ARG65543 anti-CD157 / BST1 antibody [SY11B5] FACS image
Flow Cytometry: Human peripheral blood leukocytes stained with ARG65543 anti-CD157 / BST1 antibody [SY11B5], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.
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