anti-CD160 antibody [BY55] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [BY55] recognizes CD160
反应物种: Hu
应用: FACS
特异性: The clone BY55 recognizes CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. detects both GPI-anchored and transmembrane form of CD160.
宿主: Mouse
克隆: Monoclonal
克隆号: BY55
同位型: IgM
靶点名称: CD160

CAT.NO. : ARG54231

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Size:

50 tests

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [BY55] recognizes CD160
反应物种	Hu
应用	FACS
特异性	The clone BY55 recognizes CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. detects both GPI-anchored and transmembrane form of CD160.
宿主	Mouse
克隆	Monoclonal
克隆号	BY55
同位型	IgM
靶点名称	CD160
抗原物种	Human
抗原	Human NK cell line YT2C2
偶联标记	PE
別名	BY55; Natural killer cell receptor BY55; NK28; NK1; CD antigen CD160; CD160 antigen

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液	TBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 11126 Human CD160 Swiss-port # O95971 Human CD160 antigen
基因名称	CD160
全名	CD160 molecule
背景介绍	CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.
生物功能	Receptor showing broad specificity for both classical and non-classical MHC class I molecules. [UniProt]
研究领域	Immune System antibody
预测分子量	20 kDa

检测图片 (3)

ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Human lymphocytes stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood) and ARG53782 anti-CD19 antibody [LT19] (APC) (10 µl reagent / 100 µl of peripheral whole blood).
ARG54231 anti-CD160 antibody [BY55] (PE) FACS image
Flow Cytometry: Separation of human CD160 positive B cells (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG54231 anti-CD160 antibody [BY55] (PE) (10 µl reagent / 100 µl of peripheral whole blood).

参考文献

克隆号文献

A novel 80-kD cell surface structure identifies human circulating lymphocytes with natural killer activity.

Maïza H et al.
J Exp Med., (1993)

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