anti-CD169 / Siglec 1 antibody [3B11/11] (FITC)

Key features and details

  • 产品描述: FITC-conjugated Mouse Monoclonal antibody [3B11/11] recognizes CD169 / Siglec 1
  • 反应物种: Pig
  • 应用: FACS
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 3B11/11
  • 同位型: IgG1
  • 靶点名称: CD169 / Siglec 1
  • 抗原物种: Pig
  • Brand:
CAT.NO. : ARG22858
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Product Details
概述
产品描述FITC-conjugated Mouse Monoclonal antibody [3B11/11] recognizes CD169 / Siglec 1
反应物种Pig
应用FACS
宿主Mouse
克隆Monoclonal
克隆号3B11/11
同位型IgG1
靶点名称CD169 / Siglec 1
抗原物种Pig
抗原Porcine alveolar macrophages.
偶联标记FITC
別名CD169; Siglec-1; dJ1009E24.1; Sialic acid-binding Ig-like lectin 1; SIGLEC-1; CD antigen CD169; SN; Sialoadhesin
应用说明
应用建议
应用推荐稀释比
FACSNeat
应用说明FACS: Use 10 µl of the suggested working dilution to 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.09% Sodium azide and 1% BSA
抗菌剂0.09% Sodium azide
稳定剂1% BSA
浓度0.1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称SIGLEC1
全名sialic acid binding Ig-like lectin 1, sialoadhesin
背景介绍This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
生物功能Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. [UniProt]
预测分子量183 kDa
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