anti-CD18 / LFA1 beta antibody [C71/16] (Biotin)

产品描述: Biotin-conjugated Rat Monoclonal antibody [C71/16] recognizes CD18 / LFA1 beta
反应物种: Ms
应用: ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, WB
特异性: Mouse CD18. The clone C71/16 has not been reported to inhibit cell adhesion.
宿主: Rat
克隆: Monoclonal
克隆号: C71/16
同位型: IgG2a, kappa
靶点名称: CD18 / LFA1 beta

CAT.NO. : ARG20847

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Biotin-conjugated Rat Monoclonal antibody [C71/16] recognizes CD18 / LFA1 beta
反应物种	Ms
应用	ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, WB
特异性	Mouse CD18. The clone C71/16 has not been reported to inhibit cell adhesion.
宿主	Rat
克隆	Monoclonal
克隆号	C71/16
同位型	IgG2a, kappa
靶点名称	CD18 / LFA1 beta
抗原物种	Mouse
抗原	Cell membrane glycoproteins derived from mouse BW5147 T cell lymphoma cells
偶联标记	Biotin
別名	MF17; LAD; CD antigen CD18; MFI7; MAC-1; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; LCAMB; Integrin beta-2; Complement receptor C3 subunit beta; LFA-1; CD18

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	PBS and 0.1% Sodium azide.
抗菌剂	0.1% Sodium azide
浓度	0.5 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 16414 Mouse ITGB2 Swiss-port # P11835 Mouse Integrin beta-2
基因名称	ITGB2
全名	integrin beta 2
背景介绍	This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
生物功能	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. [UniProt]
预测分子量	85 kDa
翻译后修饰	Both Ser-745 and Ser-756 become phosphorylated when T-cells are exposed to phorbol esters (PubMed:11700305). Phosphorylation on Thr-758 (but not on Ser-756) allows interaction with 14-3-3 proteins (PubMed:11700305, PubMed:16301335).

检测图片 (1)

ARG20847 anti-CD18 / LFA1 beta antibody [C71/16] (Biotin) FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG20847 anti-CD18 / LFA1 beta antibody [C71/16] (Biotin).

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