anti-CD180 / RP105 antibody [G28-8] (low endotoxin)

产品描述: Azide free and low endotoxin Mouse Monoclonal antibody [G28-8] recognizes CD180 / RP105
反应物种: Hu
应用: FACS, FuncSt, IP
特异性: The mouse monoclonal antibody G28-8 recognizes an extracellular epitope of CD180, a 95-105 kDa TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.
宿主: Mouse
克隆: Monoclonal
克隆号: G28-8
同位型: IgG1, kappa
靶点名称: CD180 / RP105

CAT.NO. : ARG42261

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Azide free and low endotoxin Mouse Monoclonal antibody [G28-8] recognizes CD180 / RP105
反应物种	Hu
应用	FACS, FuncSt, IP
特异性	The mouse monoclonal antibody G28-8 recognizes an extracellular epitope of CD180, a 95-105 kDa TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.
宿主	Mouse
克隆	Monoclonal
克隆号	G28-8
同位型	IgG1, kappa
靶点名称	CD180 / RP105
抗原物种	Human
抗原	Human tonsillar B cells.
偶联标记	Un-conjugated
別名	LY64; Radioprotective 105 kDa protein; CD180 antigen; CD antigen CD180; Lymphocyte antigen 64; RP105; Ly78

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
纯化说明	0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein.
缓冲液	PBS
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 4064 Human CD180 Swiss-port # Q99467 Human CD180 antigen
基因名称	CD180
全名	CD180 molecule
背景介绍	CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
生物功能	May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). [UniProt]
细胞定位	Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	74 kDa

检测图片 (2)

ARG42261 anti-CD180 / RP105 antibody [G28-8] (low endotoxin) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42261 anti-CD180 / RP105 antibody [G28-8] (low endotoxin) at 6 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.
ARG42261 anti-CD180 / RP105 antibody [G28-8] (low endotoxin) FACS image
Flow Cytometry: Separation of Human CD180 positive lymphocytes (red-filled) from CD180 negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG42261 anti-CD180 / RP105 antibody [G28-8] (low endotoxin) at 6 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.

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