anti-CD1a antibody [O10]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [O10] recognizes CD1a
  • 反应物种: Hu
  • 应用: FACS, ICC/IF, IHC-P, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: O10
  • 同位型: IgG1, kappa
  • 靶点名称: CD1a
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG55937
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Product Details
概述
产品描述Mouse Monoclonal antibody [O10] recognizes CD1a
反应物种Hu
应用FACS, ICC/IF, IHC-P, WB
宿主Mouse
克隆Monoclonal
克隆号O10
同位型IgG1, kappa
靶点名称CD1a
抗原物种Human
抗原Human thymus cells.
偶联标记Un-conjugated
別名R4; FCB6; CD antigen CD1a; T6; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; T-cell surface glycoprotein CD1a; CD1; HTA1
应用说明
应用建议
应用推荐稀释比
FACS1 - 2 µg/10^6 cells
ICC/IF1 - 5 µg/ml
IHC-P1 - 5 µg/ml
WB0.5 - 1 µg/ml
应用说明IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 909 Human CD1A

Swiss-port # P06126 Human T-cell surface glycoprotein CD1a

基因名称CD1A
全名CD1a molecule
背景介绍This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
生物功能Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. [UniProt]
细胞定位Cell surface
产品亮点Related products:
CD1a antibodies; Anti-Mouse IgG secondary antibodies;
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预测分子量37 kDa
检测图片 (2)
  • ARG55937 anti-CD1a antibody [O10] IHC-P image

    Immunohistochemistry: Human skin stained with ARG55937 anti-CD1a antibody [O10].

  • ARG55937 anti-CD1a antibody [O10] FACS image

    Flow Cytometry: Molt-4 cells stained with ARG55937 anti-CD1a antibody [O10] (blue); Isotype control (red).

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