anti-CD2 antibody [12-15] (PE)
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Key features and details
- 产品描述:
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- 应用:
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- 宿主:
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- 克隆号:
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- 靶点名称:
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Brand:
CAT.NO. : ARG20814
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Product Details
概述
| 产品描述 | PE-conjugated Rat Monoclonal antibody [12-15] recognizes CD2 |
|---|---|
| 反应物种 | Ms |
| 应用 | BL, FACS |
| 特异性 | Mouse CD2. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 12-15 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD2 |
| 抗原物种 | Mouse |
| 抗原 | Crude plasma membranes of ESb cells |
| 偶联标记 | PE |
| 別名 | T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD2 |
| 全名 | CD2 antigen |
| 背景介绍 | CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010] |
| 生物功能 | CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (2)
ARG20814 anti-CD2 antibody [12-15] (PE) FACS image
Flow Cytometry: BALB/c Mouse splenocytes stained with ARG20814 anti-CD2 antibody [12-15] (PE).
ARG20814 anti-CD2 antibody [12-15] (PE) FACS image
Flow Cytometry: C57BL/6 Mouse splenocytes stained with ARG20814 anti-CD2 antibody [12-15] (PE).
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