anti-CD2 antibody [HuLy-m1] (azide free)

Key features and details

  • 产品描述: Azide free Mouse Monoclonal antibody [HuLy-m1] recognizes CD2
  • 反应物种: Hu
  • 应用: FACS, ICC/IF
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: HuLy-m1
  • 同位型: IgG2b, kappa
  • 靶点名称: CD2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG41901
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Product Details
概述
产品描述Azide free Mouse Monoclonal antibody [HuLy-m1] recognizes CD2
反应物种Hu
应用FACS, ICC/IF
宿主Mouse
克隆Monoclonal
克隆号HuLy-m1
同位型IgG2b, kappa
靶点名称CD2
抗原物种Human
抗原Human thymocytes.
偶联标记Un-conjugated
別名T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2
应用说明
应用建议
应用推荐稀释比
FACS0.5 - 1 µg/10^6 cells
ICC/IF0.5 - 1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 914 Human CD2

Swiss-port # P06729 Human T-cell surface antigen CD2

基因名称CD2
全名CD2 molecule
背景介绍CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
生物功能CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt]
细胞定位Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量39 kDa
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