anti-CD200 antibody [OX-104] (APC)
![anti-CD200 antibody [OX-104] (APC)](/upload/image/products/ARG54292_FACS_1_210_205.jpg)
![anti-CD200 antibody [OX-104] (APC)](/upload/image/products/ARG54292_FACS_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
-
Brand:
CAT.NO. : ARG54292
US＄ Please choose
US＄ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [OX-104] recognizes CD200 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone OX-104 recognizes CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | OX-104 |
| 同位型 | IgG1 |
| 靶点名称 | CD200 |
| 抗原物种 | Human |
| 抗原 | Human CD200 |
| 偶联标记 | APC |
| 別名 | OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD200 |
| 全名 | CD200 molecule |
| 背景介绍 | CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization. |
| 生物功能 | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Immune System antibody |
| 预测分子量 | 31 kDa |
检测图片 (1)
ARG54292 anti-CD200 antibody [OX-104] (APC) FACS image
Flow Cytometry: Human peripheral blood stained with ARG54292 anti-CD200 antibody [OX-104] (APC) and anti-CD3 antibody (PE).
参考文献
克隆号文献
Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.
Activation of protease-activated receptor 2 induces VEGF independently of HIF-1.
FACS / Human
Differential expression of stem-cell-associated markers in human hair follicle epithelial cells.
ICC/IF / Human
New Products
