anti-CD21 antibody [BB6-11C9.6]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [BB6-11C9.6] recognizes CD21
  • 反应物种: Pig
  • 应用: FACS, IHC-Fr, IP
  • 特异性: Porcine CD21. The clone BB6-11C9.6 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 92-96% in peripheral blood, 74-98% in mesenteric lymph nodes, 97-100% in ileal Peyer’s patches (ILPP), 93-97% in spleen, and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: BB6-11C9.6
  • 同位型: IgG1, kappa
  • 靶点名称: CD21
  • Brand:
CAT.NO. : ARG21134
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Product Details
概述
产品描述Mouse Monoclonal antibody [BB6-11C9.6] recognizes CD21
反应物种Pig
应用FACS, IHC-Fr, IP
特异性Porcine CD21. The clone BB6-11C9.6 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 92-96% in peripheral blood, 74-98% in mesenteric lymph nodes, 97-100% in ileal Peyer’s patches (ILPP), 93-97% in spleen, and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
宿主Mouse
克隆Monoclonal
克隆号BB6-11C9.6
同位型IgG1, kappa
靶点名称CD21
抗原物种Pig
偶联标记Un-conjugated
別名Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor
应用说明
应用建议
应用推荐稀释比
FACSAssay-dependent
IHC-FrAssay-dependent
IPAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液BBS (pH 8.2)
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称CR2
全名complement component (3d/Epstein Barr virus) receptor 2
背景介绍CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
生物功能Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt]
预测分子量113 kDa
检测图片 (1)
  • ARG21134 anti-CD21 antibody [BB6-11C9.6] FACS image

    Flow Cytometry: Porcine peripheral blood lymphocytes stained with ARG21134 anti-CD21 antibody [BB6-11C9.6] followed by ARG21884 Goat anti-Mouse IgG1 antibody (FITC) (pre-adsorbed).

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