anti-CD21 antibody [CA2.1D6]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [CA2.1D6] recognizes CD21This antibody recognizes Canine CD21, also known as Complement receptor type 2. CD21is a cell surface antigen expressed by Canine B lymphocytes.The antigen recognised may be the Canine homologue of Human CD21, but this has not been fully confirmed.Mouse anti Canine CD21 antibody , clone CA2.1D6 also recognizes the CD21 antigen in Felids. Expression in cats is analogous to that seen in dogs with strong expression on lymphocytes, in a manner mutually exclusive with expression of CD4 or CD8. Clone CA2.1D6 also immunoprecipitates a 145kDa protein from feline lymphocytes, similar to the protein immunoprecipitated by the antibody from Canine lymphocytes (Dean et al. 1996).
  • 反应物种: Cat, Dog, Hrs
  • 应用: FACS, IHC-Fr, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: CA2.1D6
  • 同位型: IgG1
  • 靶点名称: CD21
  • 抗原物种: Dog
  • Brand:
CAT.NO. : ARG22651
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Product Details
概述
产品描述Mouse Monoclonal antibody [CA2.1D6] recognizes CD21
This antibody recognizes Canine CD21, also known as Complement receptor type 2. CD21is a cell surface antigen expressed by Canine B lymphocytes.
The antigen recognised may be the Canine homologue of Human CD21, but this has not been fully confirmed.
Mouse anti Canine CD21 antibody , clone CA2.1D6 also recognizes the CD21 antigen in Felids. Expression in cats is analogous to that seen in dogs with strong expression on lymphocytes, in a manner mutually exclusive with expression of CD4 or CD8. Clone CA2.1D6 also immunoprecipitates a 145kDa protein from feline lymphocytes, similar to the protein immunoprecipitated by the antibody from Canine lymphocytes (Dean et al. 1996).
反应物种Cat, Dog, Hrs
应用FACS, IHC-Fr, IP
宿主Mouse
克隆Monoclonal
克隆号CA2.1D6
同位型IgG1
靶点名称CD21
抗原物种Dog
偶联标记Un-conjugated
別名Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor
应用说明
应用建议
应用推荐稀释比
FACS1:100
IHC-FrAssay-dependent
IPAssay-dependent
应用说明FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl whole blood.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称CR2
全名complement component (3d/Epstein Barr virus) receptor 2
背景介绍This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
生物功能Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt]
预测分子量113 kDa
检测图片 (1)
  • ARG22651 anti-CD21 antibody [CA2.1D6] FACS image

    Flow Cytometry: Canine peripheral blood lymphocytes stained with ARG22651 anti-CD21 antibody [CA2.1D6].

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