anti-CD21 antibody [LB21]

Key features and details

产品描述: Mouse Monoclonal antibody [LB21] recognizes CD21Mouse anti Human CD21 antibody, clone LB21 recognizes the human Complement receptor type 2, also known as CD21 or the Epstein-Barr virus receptor. CD21 is a ~14 kDa cell surface glycoprotein expressed by mature B cells and by follicular dendritic cells. The molecule acts as a receptor for complement components C3d, C3dg and iC3b, as well as for Epstein Barr Virus. It forms part of a large signal transduction complex in association with CD19.
反应物种: Hu, Bov, Cat, Goat, Sheep
应用: FACS, IHC-Fr, IP
宿主: Mouse
克隆: Monoclonal
克隆号: LB21
同位型: IgG1
靶点名称: CD21
抗原物种: Human

Brand:

CAT.NO. : ARG22907

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Size:

1 ml

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*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [LB21] recognizes CD21 Mouse anti Human CD21 antibody, clone LB21 recognizes the human Complement receptor type 2, also known as CD21 or the Epstein-Barr virus receptor. CD21 is a ~14 kDa cell surface glycoprotein expressed by mature B cells and by follicular dendritic cells. The molecule acts as a receptor for complement components C3d, C3dg and iC3b, as well as for Epstein Barr Virus. It forms part of a large signal transduction complex in association with CD19.
反应物种	Hu, Bov, Cat, Goat, Sheep
应用	FACS, IHC-Fr, IP
宿主	Mouse
克隆	Monoclonal
克隆号	LB21
同位型	IgG1
靶点名称	CD21
抗原物种	Human
抗原	Human IM9 cell line.
偶联标记	Un-conjugated
別名	Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor

应用说明

应用建议

应用	推荐稀释比
FACS	Neat - 1:10
IHC-Fr	Assay-dependent
IP	Assay-dependent

应用说明

IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections.
FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl human whole blood.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified by ion exchange chromatography.
缓冲液	PBS, 0.09% Sodium azide and 1% BSA
抗菌剂	0.09% Sodium azide
稳定剂	1% BSA
浓度	25 µg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1380 Human CR2 Swiss-port # P20023 Human Complement receptor type 2
基因名称	CR2
全名	complement component (3d/Epstein Barr virus) receptor 2
背景介绍	This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
生物功能	Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt]
预测分子量	113 kDa

检测图片 (11)

ARG22907 anti-CD21 antibody [LB21] FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG22907 anti-CD21 antibody [LB21].
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Sheep anti Human LOX-1 antibody (red) and ARG22907 anti-CD21 antibody [LB21] (green). Nuclei are stained blue using DAPI. Merged image on right.
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Mouse anti Human CD1a antibody, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. C is the merged image with nuclei counterstained blue using DAPI. (High power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human spleen cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Low power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human spleen cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (High power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Medium power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (Medium power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with ARG22907 anti-CD21 antibody [LB21]. (High power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryosection stained with Mouse anti Human CD11b antibody, clone ICRF44, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. C is the merged image with nuclei counterstained blue using DAPI. (Medium power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryostection stained with Mouse anti Human CD83 antibody, clone HB15e, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. The merged image is in C with nuclei counterstained blue using DAPI. (Low power).
ARG22907 anti-CD21 antibody [LB21] IHC-Fr image
Immunohistochemistry: Human tonsil cryostection stained with Mouse anti Human CD83 antibody, clone HB15e, red in A and ARG22907 anti-CD21 antibody [LB21], green in B. The merged image is in C with nuclei counterstained blue using DAPI. (High power).