anti-CD21 antibody [SQab1728]

Key features and details

  • 产品描述: Recombinant Rabbit Monoclonal antibody [SQab1728] recognizes CD21
  • 反应物种: Hu
  • 应用: FACS, IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SQab1728
  • 同位型: IgG
  • 靶点名称: CD21
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG66206
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Product Details
概述
产品描述Recombinant Rabbit Monoclonal antibody [SQab1728] recognizes CD21
反应物种Hu
应用FACS, IHC-P
宿主Rabbit
克隆Monoclonal
克隆号SQab1728
同位型IgG
靶点名称CD21
抗原物种Human
抗原Synthetic peptide around the C‐terminus of CD21.
偶联标记Un-conjugated
別名Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor
应用说明
应用建议
应用推荐稀释比
FACS1:10
IHC-P1:200 ‐ 1:400
应用说明IHC-P: Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1380 Human CR2

Swiss-port # P20023 Human Complement receptor type 2

基因名称CR2
全名complement component (3d/Epstein Barr virus) receptor 2
背景介绍This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
生物功能Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt]
产品亮点Related products:
CD21 antibodies; CD21 ELISA Kits;
Related news:
Cancer Pathology Markers (SQ clones)
预测分子量113 kDa
检测图片 (3)
  • ARG66206 anti-CD21 antibody [SQab1728] FACS image

    Flow Cytometry: Ramos cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% TritonX-100 for 15 min. The cells were then stained with ARG66206 anti-CD21 antibody [SQab1728] (red) at 1:10 dilution in 1x PBS/1% BSA for 30 min at room temperture, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (black) was used as a control.

  • ARG66206 anti-CD21 antibody [SQab1728] IHC-P image

    Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human spleen tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.

    Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0

  • ARG66206 anti-CD21 antibody [SQab1728] IHC-P image

    Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human appendix tissue stained with ARG66206 anti-CD21 antibody [SQab1728] at 1:200 dilution.

    Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0

参考文献

Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors.

IHC-P / Human

Matsubara Shiro et al.
J Immunother Cancer.,  (2019)

publication_link

 

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