anti-CD230 / Prion protein antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes CD230 / Prion protein
  • 反应物种: Hu
  • 预测物种: Cow, Pig
  • 应用: WB
  • 特异性: Reported variants represent identical protein (NP_000302.1; NP_898902.1; NP_001073590.1; NP_001073591.1; NP_001073592.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CD230 / Prion protein
  • Brand:
CAT.NO. : ARG63963
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes CD230 / Prion protein
反应物种Hu
预测物种Cow, Pig
应用WB
特异性Reported variants represent identical protein (NP_000302.1; NP_898902.1; NP_001073590.1; NP_001073591.1; NP_001073592.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称CD230 / Prion protein
抗原物种Human
抗原C-SDYEDRYYREN
偶联标记Un-conjugated
別名GSS; PrPc; PrP33-35C; PrP27-30; Alternative prion protein; p27-30; CJD; ASCR; CD230; PrP; PRIP; KURU; AltPrP
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5621 Human PRNP

Swiss-port # F7VJQ1 Human Alternative prion protein

背景介绍The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
研究领域Developmental Biology antibody; Neuroscience antibody
预测分子量9 kDa
翻译后修饰The glycosylation pattern (the amount of mono-, di- and non-glycosylated forms or glycoforms) seems to differ in normal and CJD prion.
Isoform 2 is sumoylated with SUMO1.
检测图片 (1)
  • ARG63963 anti-CD230 / Prion protein antibody WB image

    Western blot: Human Brain lysate (35 µg protein in RIPA buffer) stained with ARG63963 anti-CD230 / Prion protein antibody at 0.3 µg/ml dilution.

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